Cryptic crossword clue
With a change of heart, contemplated prescribed drugs 9

The most common and most likely answer to this crossword clue is the 9 letter word MEDICATED

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MEDICATED mean?

MEDICATED verb
  1. To prescribe or administer medication to.

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