The most common and most likely answer to this crossword clue is the 8 letter word GINGERLY
G
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Y
More clues leading to the result GINGERLY
- Trap good, rely on moving with caution
- Taking great care, trap left for man in the country
- Carefully, leaving nothing out, take final tour in city
- Cautiously trap German lady on vacation
- With care, add spice to large curry, finally
- . Cutting line to enter with extreme caution
- With great care, drink frothy lager, avoiding a spray, ultimately
- Red lorry has contents unloaded with care
- Reddish lady after vacation with caution
Buddy explains!

The straight part
We know that "With great care" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with great care = gingerly.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GINGERLY mean?
GINGERLY adjective- Very careful or cautious.