Cryptic crossword clue
With heart essentially broken, one quits relationships 9

The most common and most likely answer to this crossword clue is the 9 letter word EQUATIONS

E
Q
U
A
T
I
O
N
S

Buddy explains!

The straight part
We know that "relationships" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case relationships = equations.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EQUATIONS mean?

EQUATIONS noun
  1. The act or process of equating two or more things, or the state of those things being equal (that is, identical).
  2. An assertion that two expressions are equal, expressed by writing the two expressions separated by an equal sign; from which one is to determine a particular quantity.
  3. A small correction to observed values to remove the effects of systematic errors in an observation.

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