Cryptic crossword clue
With justification, run away with a friend to meet heartless lady 12

The most common and most likely answer to this crossword clue is the 12 letter word LEGITIMATELY

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Buddy explains!

The straight part
We know that "With justification" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with justification = legitimately.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LEGITIMATELY mean?

LEGITIMATELY adverb
  1. In a legitimate manner, properly.

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