Cryptic crossword clue
With something large in the environment, lose out completely 9

The most common and most likely answer to this crossword clue is the 9 letter word WHOLESALE

I've seen this crossword clue in The Times
W
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Buddy explains!

The straight part
We know that "completely" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case completely = wholesale.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WHOLESALE mean?

WHOLESALE noun
  1. The sale of products, often in large quantities, to retailers or other merchants.
WHOLESALE verb
  1. To sell at wholesale.
WHOLESALE adjective
  1. Of or relating to sale in large quantities, for resale.
  2. Extensive, indiscriminate, all-encompassing; blanket.
WHOLESALE adverb
  1. In bulk or large quantity.
  2. Indiscriminately.

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