The most common and most likely answer to this crossword clue is the 5 letter word WANDS
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Buddy explains!
The straight part
We know that "With which wizards begin and end to work their magic" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with which wizards begin and end to work their magic = wands.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WANDS mean?
WANDS noun- A hand-held narrow rod, usually used for pointing or instructing, or as a traditional emblem of authority.
- (by extension) An instrument shaped like a wand, such as a curling wand.
- A magic wand.
- A stick, branch, or stalk, especially of willow.
- A card of a particular suit of the minor arcana in tarot, the wands.