Cryptic crossword clue
Without stopping, negotiate Leeds, crossing north to south

The most common and most likely answer to this crossword clue is the 7 letter word ENDLESS

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Without stopping" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case without stopping = endless.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ENDLESS mean?

ENDLESS adjective
  1. Having no end.
  2. Extending indefinitely.
  3. Without profitable end; fruitless; unsatisfying.

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