Cryptic crossword clue
Woman heading off big game, stampeding 6

The most common and most likely answer to this crossword clue is the 6 letter word MAGGIE

I've seen this crossword clue in The Times
M
A
G
G
I
E

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The straight part
We know that "Woman" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case woman = maggie.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MAGGIE mean?

MAGGIE noun
  1. One of several kinds of bird in the family Corvidae, especially Pica pica.
  2. A superficially similar Australian bird, Gymnorhina tibicen or Cracticus tibicen.

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