Cryptic crossword clue
Word, possibly Excel or PowerPoint, for certain applications 12

The most common and most likely answer to this crossword clue is the 12 letter word POLYSYLLABLE

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Buddy explains!

The straight part
We know that "Word" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case word = polysyllable.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does POLYSYLLABLE mean?

POLYSYLLABLE noun
  1. A word with more than two syllables. Sometimes used in a more restricted sense.

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