Cryptic crossword clue
Worry about printer going wrong 12

The most common and most likely answer to this crossword clue is the 12 letter word PERTURBATION

I've seen this crossword clue in The Times
P
E
R
T
U
R
B
A
T
I
O
N

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The straight part
We know that "Worry" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case worry = perturbation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PERTURBATION mean?

PERTURBATION noun
  1. Agitation; the state of being perturbed
  2. A small change in a physical system, or more broadly any definable system (such as a biological or economic system)
  3. Variation in an orbit due to the influence of external bodies

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