Cryptic crossword clue
Worst group for tackling tricky issue 8

The most common and most likely answer to this crossword clue is the 8 letter word LOUSIEST

I've seen this crossword clue in The Daily Telegraph
L
O
U
S
I
E
S
T

Buddy explains!

The straight part
We know that "Worst" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case worst = lousiest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LOUSIEST mean?

LOUSIEST adjective
  1. Remarkably bad; of poor quality, dirty, or underhanded; mean, contemptible.
  2. Infested with lice.
  3. (usually with with) Filled or packed (with something, usually bad).

Latest crossword clues with full explanations