Cryptic crossword clue
Worst part about other papers for Guardian readers?

The most common and most likely answer to this crossword clue is the 7 letter word LEFTIES

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Guardian readers?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case guardian readers? = lefties.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LEFTIES mean?

LEFTIES noun
  1. One who is left-handed.
  2. One who has left-wing political views.
  3. One's left testicle.

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