The most common and most likely answer to this crossword clue is the 6 letter word SIGNOR
S
I
G
N
O
R
More clues leading to the result SIGNOR
- Title, something conveying meaning to the rank and file
- Some Neapolitans ignoring fellow from Rome?
- Continental gent to engage troops
- Sons endlessly cold-shoulder Italian
- Italian makes gesture on the other hand
- Character killing wife in fight about an Italian man
- Write one's name or address for Pavarotti
- Express ignorance about Italian’s title
- Italian man grins strangely — oxygen restricted
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SIGNOR mean?
SIGNOR noun- A courtesy title for a man of Italian origin.