Cryptic crossword clue
Writer’s block coming on? Apply liquid! 6

The most common and most likely answer to this crossword clue is the 6 letter word DAMPEN

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The straight part
We know that "Apply liquid" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case apply liquid = dampen.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DAMPEN mean?

DAMPEN verb
  1. To make damp or moist; to make slightly wet.
  2. To become damp or moist.
  3. To depress; to check; to make dull; to lessen.
  4. To become damped or deadened.

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