Cryptic crossword clue
Wrong treatment — not the first to cause extreme suffering 7

The most common and most likely answer to this crossword clue is the 7 letter word TORTURE

I've seen this crossword clue in The Guardian
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does TORTURE mean?

TORTURE noun
  1. Intentional causing of somebody's experiencing agony
  2. The "suffering of the heart" imposed by one on another, as in personal relationships
  3. (often as "absolute torture") stage fright, severe embarrassment
TORTURE verb
  1. To intentionally inflict severe pain or suffering on (someone).

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