The most common and most likely answer to this crossword clue is the 4 letter word LUCK
L
U
C
K
Buddy explains!

The straight part
We know that "chance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case chance = luck.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LUCK mean?
LUCK noun- Something that happens to someone by chance, a chance occurrence, especially a favourable one.
- A superstitious feeling that brings fortune or success.
- Success.
- The results of a random number generator.
- To succeed by chance.
- To rely on luck.
- To carry out relying on luck.