Cryptic crossword clue
Yet pairs splitting up may lead to acrimony 8

The most common and most likely answer to this crossword clue is the 8 letter word ASPERITY

I've seen this crossword clue in Financial Times
A
S
P
E
R
I
T
Y


Buddy explains!

The straight part
We know that "acrimony" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case acrimony = asperity.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ASPERITY mean?

ASPERITY noun
  1. Roughness as of stone or weather.
  2. Harshness, as of temper.
  3. Something that is harsh and difficult to endure.
  4. A part of a geological fault line that does not move.

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