Cryptic crossword clue
You and I are, or used to be 4

The most common and most likely answer to this crossword clue is the 4 letter word WERE

I've seen this crossword clue in The Daily Telegraph
W
E
R
E


Buddy explains!

The straight part
We know that "You and I are/used to be" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case you and i are/used to be = were.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WERE mean?

WERE noun
  1. A man, a husband
  2. A fine for slaying a man; weregild.
  3. The collective name for any kind of person that changes into another form under certain conditions, including the werewolf.

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