Cryptic crossword clue
You and I with strict, odd issues to bring in the customs of the US and UK, say 10

The most common and most likely answer to this crossword clue is the 10 letter word WESTERNISE

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Buddy explains!

The straight part
We know that "to bring in the customs of the US and UK, say" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to bring in the customs of the us and uk, say = westernise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WESTERNISE mean?

WESTERNISE verb
  1. To make something western in character.

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