The most common and most likely answer to this crossword clue is the 10 letter word ABSOLUTELY
I've seen this crossword clue in The Guardian
A
B
S
O
L
U
T
E
L
Y
More clues leading to the result ABSOLUTELY
- I agree to use all, by recycling
- Quite obtuse, all jerks on telly, ultimately
- How despots rule, without doubt
- Sure wobbly as belly out!
- Beast you’ll remove without question
- You bet positively
- Without a doubt, skilfully covers note on musical instrument
- Totally awful, lousy table
- Lout by ales will get drunk of course
- You’ll be sat puzzling, no question!
Buddy explains!

The straight part
We know that "no question!" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case no question! = absolutely.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ABSOLUTELY mean?
ABSOLUTELY adverb- In an absolute or unconditional manner; utterly, positively, wholly.
- Independently; viewed without relation to other things or factors.
- (grammar) In a manner that does not take an object.
- Yes; certainly; expression indicating strong agreement.