The most common and most likely answer to this crossword clue is the 8 letter word ORIENTAL
I've seen this crossword clue in The Guardian
O
R
I
E
N
T
A
L
More clues leading to the result ORIENTAL
- Relation dispatched from the east
- Poor relation from the east
- Relation flying from the east
- Nothing in London and Paris ahead of endless discussion about China?
- Gold cases of incense, not all from the east
- No regret for Piaf in smearing of alto from 1 down, say?
- Zero cost for tenants, including one from distant region
- Poor relation from east Asia
- Eastern trail one meandered
- First quitting heroin, Rocky gets high mostly from E?
Buddy explains!

The straight part
We know that "from distant region" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case from distant region = oriental.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ORIENTAL mean?
ORIENTAL noun- A precious stone, especially an orient pearl.
- A member or descendant of the peoples and cultures of the Orient.
- A lily cultivar of a widely varied group, with strong scent.
- A person from the eastern region of a place.
- Of a pearl or other precious stone: having a superior lustre.
- Pertaining to the eastern part of the sky; happening before sunrise.
- Happening in the eastern part of a given place or location.
- Pertaining to the regions east of the Mediterranean, beyond the Roman Empire or the early Christian world; of the Near East, the Middle East or the Far East, now especially relating to East Asia.
- Designating various types of aromatic tobacco grown in Turkey and the Balkans.