Cryptic crossword clue
Zinfandel lacking body bottled in mass makes hissing sound 6

The most common and most likely answer to this crossword clue is the 6 letter word SIZZLE

S
I
Z
Z
L
E

Buddy explains!

The straight part
We know that "hissing sound" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hissing sound = sizzle.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SIZZLE mean?

SIZZLE noun
  1. The sound of water hitting a hot surface
  2. Zing, zip, or pizazz; excitement.
SIZZLE verb
  1. To make the sound of water hitting a hot surface.
  2. To be exciting or dazzling.

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