Cryptic crossword clue
500 more lousy boxes with devious puzzle 10

The most common and most likely answer to this crossword clue is the 10 letter word WORDSEARCH

I've seen this crossword clue in The Guardian
W
O
R
D
S
E
A
R
C
H

Buddy explains!

The straight part
We know that "puzzle" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case puzzle = wordsearch.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WORDSEARCH mean?

WORDSEARCH noun
  1. (games) A word game consisting of a grid of letters, the aim of which is to find an array of given words hidden within the grid.

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