The most common and most likely answer to this crossword clue is the 6 letter word ATHENE
I've seen this crossword clue in The Times
A
T
H
E
N
E
More clues leading to the result ATHENE
- Goddess indicating sequence of characters in faerie
- Article about the eastern goddess of wisdom
- She was a goddess at that time in A&E
- Goddess putting second and third of 21 in order?
- Goddess ‘as old-fashioned vitality, not half!
- Biddy introduced to one Greek goddess or another
- Wise Olympian subsequently enters races alternately
- Goddess soon afterward in hospital department?
- Articles about heartless Eurasian goddess
- Helping to make Gaia the New Age goddess
Buddy explains!
The straight part
We know that "goddess of wisdom" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case goddess of wisdom = athene.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.