The most common and most likely answer to this crossword clue is the 9 letter word CARTESIAN
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More clues leading to the result CARTESIAN
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The cryptic/wordplay part
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What does CARTESIAN mean?
CARTESIAN adjective- Of, or pertaining to, Descartes, his mathematical methods, or his philosophy, especially with regard to its emphasis on logical analysis and its mechanistic interpretation of physical nature.
- Of, or pertaining to, co-ordinates based on mutually orthogonal axes.