The most common and most likely answer to this crossword clue is the 4 plus 3 plus 5 letter word TAKE THE WHEEL
T
A
K
E
T
H
E
W
H
E
E
L
More clues leading to the result TAKE THE WHEEL
Buddy explains!
The straight part
We know that "Assume command," is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case assume command, = take the wheel.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.