Cryptic crossword clue
Bill upset in necklace perhaps causing inflammation 9

The most common and most likely answer to this crossword clue is the 9 letter word CHILBLAIN

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Buddy explains!

The straight part
We know that "inflammation" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case inflammation = chilblain.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CHILBLAIN mean?

CHILBLAIN noun
  1. An itchy purple red inflammation of the skin, especially of the hands, feet and ears, occurring when capillaries below the skin are damaged by exposure to cold weather.

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