Cryptic crossword clue
Chemical — a rich source 5

The most common and most likely answer to this crossword clue is the 5 letter word AMINE

A
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Buddy explains!

The straight part
We know that "Chemical" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case chemical = amine.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AMINE mean?

AMINE noun
  1. A functional group formally derived from ammonia by replacing one, two or three hydrogen atoms with hydrocarbon or other radicals.
  2. Any organic compound containing an amine functional group.

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