The most common and most likely answer to this crossword clue is the 6 letter word DIOXIN
I've seen this crossword clue in Financial Times
D
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More clues leading to the result DIOXIN
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The cryptic/wordplay part
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What does DIOXIN mean?
DIOXIN noun- Any of a broad range of toxic or carcinogenic halogenated polycyclic compounds that occur as byproducts of herbicides.
- The parent compound, dibenzo-p-dioxin, in which two benzene rings are connected vio two oxygen atoms; oxanthrene.
- The unsaturated six-membered heterocycle having four carbon atoms, two oxygen atoms and two double bonds.