Cryptic crossword clue
Condition of a disco is deplorable 8

The most common and most likely answer to this crossword clue is the 8 letter word ACIDOSIS

A
C
I
D
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I
S

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The straight part
We know that "Condition" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case condition = acidosis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACIDOSIS mean?

ACIDOSIS noun
  1. An abnormally increased acidity of the blood.

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