Cryptic crossword clue
Corpulent guide, terribly weary 8

The most common and most likely answer to this crossword clue is the 8 letter word FATIGUED

I've seen this crossword clue in The Guardian
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More clues leading to the result FATIGUED

Buddy explains!

The straight part
We know that "weary" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case weary = fatigued.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FATIGUED mean?

FATIGUED verb
  1. To tire or make weary by physical or mental exertion
  2. To wilt a salad by dressing or tossing it
  3. To lose so much strength or energy that one becomes tired, weary, feeble or exhausted
  4. (of a material specimen) to undergo the process of fatigue; to fail as a result of fatigue.
FATIGUED adjective
  1. Tired; weary.

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