Cryptic crossword clue
Dire end to time in hospital unit covered in muck 8

The most common and most likely answer to this crossword clue is the 8 letter word BEGRIMED

I've seen this crossword clue in The Daily Telegraph
B
E
G
R
I
M
E
D

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BEGRIMED mean?

BEGRIMED verb
  1. To make something dirty; to soil.
BEGRIMED adjective
  1. Dirty, soiled, grimy.

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