The most common and most likely answer to this crossword clue is the 2 plus 4 plus 4 letter word IN YOUR FACE
I've seen this crossword clue in Financial Times
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More clues leading to the result IN YOUR FACE
Buddy explains!
The straight part
We know that "Direct/location of solver’s nasal and buccal cavities" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case direct/location of solver’s nasal and buccal cavities = in your face.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does IN YOUR FACE mean?
IN YOUR FACE adjective- Aggressively or blatantly confrontational