Cryptic crossword clue
Hope sentence begins with a temporal indication 4,10

The most common and most likely answer to this crossword clue is the 4 plus 10 letter word LIFE EXPECTANCY

I've seen this crossword clue in Financial Times
L
I
F
E
E
X
P
E
C
T
A
N
C
Y

Buddy explains!

The straight part
We know that "a /temporal indication" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a /temporal indication = life expectancy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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