The most common and most likely answer to this crossword clue is the 7 letter word CAMPARI
I've seen this crossword clue in The Times
C
A
M
P
A
R
I
More clues leading to the result CAMPARI
- Intoxicating substance affected air supply
- Skipping starter of seafood, getting in a little red aperitif
- Paramedic working with journalist rejected drink
- I followed confusing RAC map to get drink
- Pair out on the river, having a drink
- Drink in the fresh air next to tents
- Drink party almost dry
- Italian liqueur one consumed in holiday accommodation on Rhode Island
- A person with a seat in vehicle gets one drink
Buddy explains!
The straight part
We know that "Intoxicating substance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case intoxicating substance = campari.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.