The most common and most likely answer to this crossword clue is the 6 plus 3 plus 6 letter word SUPPLY AND DEMAND
I've seen this crossword clue in The Guardian
S
U
P
P
L
Y
A
N
D
D
E
M
A
N
D
Buddy explains!
The straight part
We know that "Law of give and take?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case law of give and take? = supply and demand.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.