Cryptic crossword clue
Nervously ran into river in very cold region? 3,5

The most common and most likely answer to this crossword clue is the 3 plus 5 letter word FAR NORTH

I've seen this crossword clue in Independent
F
A
R
N
O
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H

Buddy explains!

The straight part
We know that "very cold region?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case very cold region? = far north.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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