The most common and most likely answer to this crossword clue is the 8 letter word CHECK-IN
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More clues leading to the result CHECK-IN
Buddy explains!

The straight part
We know that "what may happen at hotel" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case what may happen at hotel = check-in.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CHECK-IN mean?
CHECK-IN noun- The act of checking in at a hotel, airport, etc.
- The submission of source code or other material to a source control repository.