Cryptic crossword clue
Place to unburden dreadful lesson of Cain 12

The most common and most likely answer to this crossword clue is the 12 letter word CONFESSIONAL

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Buddy explains!

The straight part
We know that "Place to unburden" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case place to unburden = confessional.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONFESSIONAL mean?

CONFESSIONAL adjective
  1. In the manner or style of a confession.
  2. Officially practicing a particular religion, as a state or organization. See confessionalism 1.
CONFESSIONAL noun
  1. (Roman Catholic church) A small room where confession—the sacrament of reconciliation—is performed by a priest.
  2. A confession.

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