The most common and most likely answer to this crossword clue is the 7 letter word PYRRHIC
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Buddy explains!
The straight part
We know that "Primarily, practically, your really resolute hardship is counter-productive" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case primarily, practically, your really resolute hardship is counter-productive = pyrrhic.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PYRRHIC mean?
PYRRHIC adjective- Of or relating to Pyrrhus (319/318–272 BC), Greek general and statesman.
- Achieved at too great a cost or detriment to have been worthwhile (as a victory, accomplishment, etc).
- An Ancient Greek war dance.
- A metric foot with two short or unaccented syllables.
- Of or characterized by pyrrhics (metrical feet with two short syllables).
- Relating to Pyrrhus, a Macedonian king, or some of his costly victories he had while fighting Rome.