Cryptic crossword clue
Soft stuff, unpleasant matter in hair 6

The most common and most likely answer to this crossword clue is the 6 letter word PAPPUS

P
A
P
P
U
S

Buddy explains!

The straight part
We know that "hair" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hair = pappus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PAPPUS mean?

PAPPUS noun
  1. The markedly reduced sepals of an Asteraceae floret that take the form of trichomes or scale attached to the ovary or seed.
  2. The first hair on the chin.

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