Cryptic crossword clue
Standing between two streets, Archie is most uptight 10

The most common and most likely answer to this crossword clue is the 10 letter word STARCHIEST

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Buddy explains!

The straight part
We know that "most uptight" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most uptight = starchiest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STARCHIEST mean?

STARCHIEST adjective
  1. Of or pertaining to starch.
  2. Containing starch.
  3. Having the quality of fabric starch as applied to fabric; stiff, hard; starched.
  4. Having a starched personality; stiffly formal.

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