Cryptic crossword clue
U-U-U-U like some meat? That’s a huge blow! 6,6

The most common and most likely answer to this crossword clue is the 6 plus 6 letter word DOUBLE WHAMMY

I've seen this crossword clue in The Guardian
D
O
U
B
L
E
W
H
A
M
M
Y

Buddy explains!

The straight part
We know that "a huge blow" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a huge blow = double whammy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

Latest crossword clues with full explanations