The most common and most likely answer to this crossword clue is the 6 letter word SEXISM
I've seen this crossword clue in The Guardian
S
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X
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More clues leading to the result SEXISM
Buddy explains!
The straight part
We know that "discrimination" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case discrimination = sexism.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEXISM mean?
SEXISM noun- The belief that people of one sex or gender are inherently superior to others.
- Discrimination or different treatment (e.g. in job opportunities) based on sex or gender.
- Attitudes or actions that are based on or promote the expectation that people adhere to stereotypical social roles (gender roles) based on sex.